How Ketamine’s Dependency Risk Measures Up Against other drug substances

Author : Harry Jamess | Published On : 25 Feb 2026

How Ketamine Operates


A dissociative anesthetic used to relieve pain and before surgery is ketamine. Ketamine blocks NMDA receptors that support memory and critical thinking, in contrast to other opioids that alter pain receptors or raise dopamine levels in the brain. We refer to this phenomenon as the K-holes effect. People frequently look up information about how addictive ketamine is and how to get rid of it. To gain a thorough grasp of their effects, we shall compare ketamine with other substances in this essay.

 

Ketamine vs. Other Drugs

When compared with other addictive substances, ketamine has a unique profile. It does not severely affect physical health as compared to others, but its mental health effect is quite powerful. The table below gives a detailed comparison between ketamine and other addictive substances.

 

Drug

Physical Hook

Psychological Hook

Primary Risk

Heroin

Extremely High

Extremely High

Overdose / Respiratory failure

Cocaine

Low

Extremely High

Heart attack / Intense "crash."

Ketamine

Low

Moderate to High

Bladder damage 

Alcohol

High

High

Organ failure 

 

The Impact on Mental Health


Similar to the symptoms of alcohol withdrawal, there are no physical health problems associated with ketamine addiction. Instead, the central nervous system is impacted. The patient is unable to distinguish between the real and imagined worlds due to the hallucinogenic impact. Every time a patient encounters a challenging circumstance, they experience strong cravings and use the medication to get out of it. The brain quickly develops tolerance as a result of frequent ingestion. Consequently, in order to have the same effect, the patient consistently takes larger doses than before. It is necessary to know the effects on mental health so that it will be easy for you to identify signs early for better ketamine addiction treatment.

 

Therapy VS. Self healing

In rehab centers, doctors give small, safe doses in a prescribed time interval, so there is a low risk of getting hooked. Some people try to self-heal instead of going for professional treatment. They take doses after doses in short time intervals. These habits make them more addicted than healing.

 

The Body's Long-Term Impact


Even if surgery could be necessary in an emergency, long-term ketamine use combined with an overdose causes Ketamine Cystitis, which seriously damages the bladder. It also severly affect the performance of the brain. Regular consumption may cause memory loss and make it harder to focus on everyday tasks.

 

The Method for Quitting


Reducing ketamine addiction has a greater impact on mental health than physical health. The brain attempts to restructure its system and functioning after a period of withdrawal. After keeping an eye on their patients' health, some treatment facilities offer specialized ketamine addiction recovery programsIdentification of the trigger points is aided by several therapies, including CBT. In addition, many mental therapies are administered to promote mental well-being and speedy healing. Regular check-ups are also necessary for the patient's health monitoring and direction.

Resource-  https://sites.google.com/view/how-addictive-is-ketamine/