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Bridging the Gap: How the Global Protein Purification and Isolation Market is Expanding Access to Ca

Author : Bhushan S | Published On : 13 May 2024

The global protein purification and isolation market is expected to grow significantly, with a valuation expected to exceed US$24.76 billion by 2033. With a Compound Annual Growth Rate (CAGR) of 10.6%, this substantial rise builds on the market’s estimated size of US$9.03 billion in 2023.

In biochemical research, biopharmaceutical development, and industrial biotechnology, protein purification and isolation are essential procedures that allow scientists and researchers to obtain pure and biologically active proteins for a variety of applications, such as structural biology, proteomics, and drug discovery.

Protein purification and isolation are crucial processes in biochemical research, biopharmaceutical production, and clinical diagnostics that enable researchers and clinicians to separate, purify, and analyze proteins for a range of applications. These processes include isolating target proteins from complex biological materials, such as cell lysates, tissue homogenates, or fermentation broths, in order to obtain extremely pure and bioactive protein fractions.

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Despite several challenges, the protein separation and purification sector is expanding. Because protein architectures vary so much, it can be difficult to achieve high purity and yield throughout the purification process. Certain proteins are difficult to purify by nature due to their stability, solubility, or molecular interactions. The expensive development and application of complex purification procedures and equipment is another barrier. It can be costly to investigate, develop, and scale up purification technologies, particularly for small biotech businesses or university research groups. The protein purification and separation industry’s long-term performance hinges on finding creative technologies, optimizing processes, and coming up with cost-effective solutions to these issues.

Key Takeaways from the Protein Purification and Isolation Market:

  • With a commanding market share of 31.9% in 2023, the United States solidifies its position as a leading protein purification and isolation industry player.
  • Germany holds a share of 6.8% in 2023, reflecting its presence and contribution to the protein purification and isolation industry.
  • Japan captures a share of 7.2% in 2023, indicating a strong market presence and growing demand for protein purification and isolation solutions in the country.
  • Australia exhibits a promising growth potential with a compound annual growth rate (CAGR) of 9.3% during the forecast period, showcasing increasing adoption of protein purification and isolation technologies in the country.
  • With an impressive CAGR of 16.5% during the forecast period, China signifies a booming protein purification and isolation market, reflecting high demand and significant growth opportunities in the region.
  • India presents a thriving protein purification and isolation market, projected to achieve a CAGR of 15.1% during the forecast period, highlighting a rapid adoption of these technologies in the country.
  • Protein interaction studies capture a substantial market share of 32.70% in 2023, indicating its significance and widespread adoption in various research and biotechnological applications.
  • Academic and research institutes dominate the market with a commanding 50.20% market share in 2023, reflecting their strong involvement and demand for protein purification and isolation techniques for various scientific studies and advancements.

Competitive Landscape for the Protein Purification and Isolation Market:

Protein purification and isolation market participants are attempting to increase their foothold by implementing tactics like new product launches, geographic expansion, mergers, acquisitions, and partnerships. For instance, in September 2021, GE Healthcare Life Sciences agreed to purchase BK Medical from Altaris Capital Partners, LLC, for USD 1.45 billion in cash. The deal was announced in December 2021.

In March of 2022, Thermo Fisher Scientific and Symphogen announced they would continue working together to supply biopharmaceutical R&D laboratories with platform workflows for quality monitoring and simplified characterization of complex therapeutic proteins. Thermo Fisher Scientific’s dominance in the protein purification and separation market is expected to be preserved thanks to this.

Global Protein Purification and Isolation Market Key Players:

  • Merck KGaA
  • Thermo Fischer Scientific, Inc.
  • GE Healthcare Life Sciences
  • Qiagen NV.
  • Sigma-Aldrich Corporation
  • Agilent Technologies
  • Bio-Rad Laboratories, Inc.
  • Promega Corporation

Protein Purification and Isolation Market by Segmentation:

By Product:

  • Instruments
  • Consumables
  • Kits
  • Reagents
  • Columns
  • Magnetic Beads
  • Resins
  • Others

By Technology:

  • Ultrafiltration
  • Precipitation
  • Chromatography
  • Ion Exchange Chromatography
  • Affinity Chromatography
  • Reversed-Phase Chromatography
  • Size Exclusion Chromatography
  • Hydrophobic Interaction Chromatography
  • Electrophoresis
  • Gel Electrophoresis
  • Isoelectric Focusing
  • Capillary Electrophoresis
  • Western Blotting
  • Others

By Application:

  • Drug Screening
  • Biomarker Discovery
  • Protein-protein Interaction Studies
  • Diagnostics

By End Use:

  • Academic and Research Institutes
  • Hospitals
  • Pharmaceutical and Biotechnological Companies
  • CROs

By Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • Middle East and Africa