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Successes and challenges on the other side of the blood-brain barrier

Brain tumours are a heterogenous group of diseases, with over 100 types and subtypes, benign and malignant. Figure 1 shows the types of malignant brain tumours operated on most commonly at Royal Melbourne and Melbourne Private Hospitals, both busy tertiary referral centres.

In this paper, we focus on adult malignant brain tumours, accounting for 1.5% of all new cancers diagnosed annually in Australia. The most recent Australian Institute of Health and Welfare cancer incidence and mortality data indicate that in 2010, 1680 Australians were diagnosed with a malignant brain tumour and in 2011, over 1200 died from the disease, a sobering observation that incidence is closely matched by mortality


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